Figure 1
From: Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice
JAK2V617F mice develop cardiomegaly associated with increased blood cell counts. Photos of hearts from typical control and JAK2V617F transgenic mice at age of 40–45 weeks are shown (A). Bar graphs represent average heart mass (B), body mass (C), heart/body ratio (D), red blood cell counts (E), and platelet counts (F) of control (open bar) and JAK2V617F transgenic (closed bar) mice at indicated ages. Error bars denote standard deviation (n ≥10). * P <0.05, **P < 0.01, ***P < 0.001.