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Table 1 Clinical and laboratory characteristics of the patients before and after SSAE procedures

From: Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria

Pt Age at PNH diagnosis (year) Spleen size in cm before SSAE Abdominal pain prior to procedure Representative blood counts before SSAE % GPI-negative blood cells   SSAE procedures Plt count post treatment Spleen size in cm post procedure  
HGB g/dl Abs Neut × 10-3/μl Plts × 10-3/μl PMNs RBCs Bone marrow findings Yr of first procedure Number of procedures Complications Follow-up, yrs
1 30 (1993) 21 Frequent attacks 10.5 1.4 42 52 15 Hypercellular; megakaryocyte aggregates 2000 3 Severe left-sided abdominal pain 123 12 12
2 18 (1990) 19 Frequent attacks 10 2.3 19 95 72 Hypocellular; megakaryocytes reduced 2005 2 Pain; large left sided pleural effusion, resolved with thoracentesis, 12 12 7*
3 27 (1989) 36 No 10.3 1.5 14 75 47 Erythroid hyperplasia; megakaryocytes adequate 2001 1 Abdominal pain 35 NA 11
4 26 (1998) 22 Occasional attacks 7.7 0.9 <10 97 55 Normocellular; megakaryocytes adequate 2009 3 Uneventful 80-100 12 3.5
  1. *In 2009 this Patient underwent successful allogeneic stem cell transplantation from an unrelated donor.