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Table 1 Demographic and clinical characteristics within the five categories of platelet counts

From: Lower circulating platelet counts and antiplatelet therapy independently predict better outcomes in patients with head and neck squamous cell carcinoma

  Platelet count categories
Variable Low (1-149) N = 67 Low normal (150-229) N = 361 Mid normal (230-314) N = 379 High normal (315-399) N = 169 High (≥400) N = 75 p-value
Age-yrs. Mean (SD) 60.0 (10.7) 61.0 (10.8) 58.4 (11.9) 58.0 (10.8) 58.2 (11.5) 0.009
Male-no. (%) 55 (82) 302 (84) 273 (72) 117 (69) 53 (71) <0.0001
Race-no. (%)       <0.0001
Caucasian 48 (72) 287 (79) 293 (77) 116 (69) 42 (56)  
African American 18 (27) 67 (19) 83 (22) 52 (31) 33 (44)  
Other 1 (1.5) 7 (2) 3 (1) 1 (0.5) 0 (0)  
Smoker-no. (%)       <0.0001
Never 6 (9) 63 (19) 67 (19) 18 (11) 4 (6)  
Former 20 (32) 125 (38) 111 (32) 40 (25) 14 (20)  
Current 37 (59) 145 (43) 173 (50) 102 (64) 52 (74)  
Alcohol - no. (%)       0.02
Never 17 (27) 99 (30) 108 (29) 36 (23) 7 (10)  
Former 13 (20) 55 (17) 54 (14) 26 (17) 9 (14)  
Current 34 (53) 174 (53) 177 (46) 94 (60) 50 (76)  
Stage       0.034
I 6 (11) 42 (15) 42 (14) 8 (7) 5 (8)  
II 9 (17) 37 (13) 35 (12) 10 (8) 4 (6)  
III 9 (17) 60 (21) 50 (17) 18 (15) 9 (14)  
IV 29 (55) 147 (51) 168 (57) 87 (71) 47 (72)  
Grade       0.90
Undetermined 20 (30) 106 (29) 103 (27) 42 (25) 16 (21)  
I. Well Differentiated 9 (13) 43 (12) 49 (13) 18 (11) 8 (11)  
II. Moderately 29 (43) 152 (42) 164 (43) 80 (47) 41 (55)  
III. Poorly or undifferentiated 9 (13) 59 (17) 63 (17) 29 (17) 10 (13)  
Primary Site       0.09
Oral 34 (51) 171 (47) 190 (50) 100 (59) 34 (45)  
Pharynx 13 (19) 101 (28) 107 (28) 42 (25) 18 (24)  
Larynx 20 (30) 89 (25) 82 (22) 27 (16) 23 (31)  
Post-diagnosis NSAIDs and/or Anti-platelets       0.33
No no. (%) 48 (72) 259 (72) 277 (73) 133 (79) 60 (80)  
Yes no. (%) 19 (28) 102 (28) 102 (27) 36 (21) 15 (20)  
  1. All variables had complete data (n = 1051) except: smoking status (n = 977), alcohol use (n = 953), clinical stage (n = 822) and tumor grade, where the undetermined category accounted for n = 247 cases.