Figure 4
Expression of target genes of Wnt/β-catenin signaling are up-regulated in hBM-MSC-conditioned ALCs. (A) The mRNA levels of Cyclin D1, c-Myc and Survivin expressed in ALCs cultured alone or with hBM-MSCs. (B) The mRNA levels of Cyclin D1, c-Myc and Survivin expressed in Reh and Kasumi-1 cells after transfection with gal-3 shRNA or vector, cultured alone or with hBM-MSCs. (C) Cell cycle analysis of Reh and Kasumi-1 cells after transfection with gal-3 shRNA or vector, cultured alone or with hBM-MSCs.