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Table 1 Clinicopathologic associations of GAS5 expression in lung adenocarcinoma

From: The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression

Clinical parameters No. of cases Relative GAS5 expression
   Low High P valuea
Age     0.500
>60 years 39 19 20  
≤60 years 33 17 16  
Gender     0.479
Male 37 20 17  
Female 35 16 19  
Smoking     0.151
Non-smoker 42 18 24  
Smoker 30 18 12  
Differentiation     0.03**
Well 26 14 12  
Moderate-Poor 46 36 10  
Maximum diameter     0.03**
<3 cm 26 14 12  
≥3 cm 46 36 10  
Lymphatic metastasis     0.131
Absent 41 27 14  
Present 31 25 6  
Distal metastasis     1.000
M0 68 34 34  
M1 4 2 2  
TNM stage     0.047**
I–II 51 32 19  
III–IV 21 18 3  
CEA     0.583
Positive 34 16 18  
Negative 38 18 20  
CA19-9     0.500
Positive 39 19 20  
Negative 33 17 16  
CA125     0.577
Positive 29 16 13  
Negative 43 29 24  
  1. aChi-squared test. **P < 0.05.
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Journal of Hematology & Oncology

ISSN: 1756-8722

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