|
Proteins
|
Cellular functions
|
|---|
|
Endocytosis
|
Phagocytosis
|
Filopodium
|
Lamellipodium
|
Cytokinesis
|
Adhesion
|
Podosome
|
|---|
|
1. CIP4 subfamily
| | | | | | | |
|
CIP4
|
√
|
N/A
|
N/A
|
√
|
N/A
|
N/A
|
N/A
|
|
FBP17
|
√
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
√
|
|
Toca-1
|
√
|
N/A
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
|
2. FCHOs subfamily
| | | | | | | |
|
FCHO1
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
FCHO2
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
3. srGAPs subfamily
| | | | | | | |
|
srGAP1
|
N/A
|
N/A
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
|
srGAP2
|
N/A
|
N/A
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
|
srGAP3
|
N/A
|
N/A
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
|
4. PACSINs subfamily
| | | | | | | |
|
PACSIN1
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
PACSIN2
|
√
|
N/A
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
|
PACSIN3
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
5. PSTPIPs subfamily
| | | | | | | |
|
PSTPIP1
|
√
|
N/A
|
N/A
|
√
|
√
|
√
|
N/A
|
|
PSTPIP2
|
N/A
|
N/A
|
√
|
N/A
|
N/A
|
N/A
|
√
|
|
6. FCHSDs subfamily
| | | | | | | |
|
FCHSD1
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
FCHSD2
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
7. FES/FER subfamily
| | | | | | | |
|
FES
|
N/A
|
N/A
|
N/A
|
√
|
N/A
|
N/A
|
N/A
|
|
FER
|
N/A
|
N/A
|
N/A
|
√
|
N/A
|
√
|
N/A
|
|
8. NOSTRIN subfamily
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
N/A
|
|
9. GAS7 subfamily
|
N/A
|
N/A
|
√
|
N/A
|
N/A
|
N/A
|
N/A
|
- F-BAR proteins are implicated in various biological functions via interaction with specific binding partners. For F-BAR protein abbreviations, refer to Figure 1.
