Skip to main content

Table 1 Biological functions of F-BAR subfamilies

From: F-BAR family proteins, emerging regulators for cell membrane dynamic changes—from structure to human diseases

Proteins Cellular functions
Endocytosis Phagocytosis Filopodium Lamellipodium Cytokinesis Adhesion Podosome
1. CIP4 subfamily        
 CIP4 N/A N/A N/A N/A N/A
 FBP17 N/A N/A N/A N/A
 Toca-1 N/A N/A N/A N/A N/A
2. FCHOs subfamily        
 FCHO1 N/A N/A N/A N/A N/A N/A
 FCHO2 N/A N/A N/A N/A N/A N/A
3. srGAPs subfamily        
 srGAP1 N/A N/A N/A N/A N/A N/A
 srGAP2 N/A N/A N/A N/A N/A N/A
 srGAP3 N/A N/A N/A N/A N/A N/A
4. PACSINs subfamily        
 PACSIN1 N/A N/A N/A N/A N/A N/A
 PACSIN2 N/A N/A N/A N/A N/A
 PACSIN3 N/A N/A N/A N/A N/A N/A
5. PSTPIPs subfamily        
 PSTPIP1 N/A N/A N/A
 PSTPIP2 N/A N/A N/A N/A N/A
6. FCHSDs subfamily        
 FCHSD1 N/A N/A N/A N/A N/A N/A
 FCHSD2 N/A N/A N/A N/A N/A N/A
7. FES/FER subfamily        
 FES N/A N/A N/A N/A N/A N/A
 FER N/A N/A N/A N/A N/A
8. NOSTRIN subfamily N/A N/A N/A N/A N/A N/A
9. GAS7 subfamily N/A N/A N/A N/A N/A N/A
  1. F-BAR proteins are implicated in various biological functions via interaction with specific binding partners. For F-BAR protein abbreviations, refer to Figure 1.