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Table 1 Immunocytochemical staining for NLK in samples from NSCLC and benign pulmonary disease

From: NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin

Characteristic No. of samples No. of positive samples (%) Statistical significance
Normal lung tissues 92 4 (4.4) p = 0.000
Primary tumors of NSCLC 121 62 (51.2)
Pathology    
Squamous cell carcinoma 61 31 (50.8) p = 0.926
Adenocarcinoma 60 31 (51.7)
Tumor size (T stage)    
T1/ T2 98 45 (45.0) p = 0.016
T3/ T4 23 17 (73.3)
Lymph node metastasis    
Positive 60 34 (56.7) p = 0.236
Negative 61 28 (45.9)