Table 1 Immunocytochemical staining for NLK in samples from NSCLC and benign pulmonary disease
From: NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin
Characteristic | No. of samples | No. of positive samples (%) | Statistical significance |
|---|---|---|---|
Normal lung tissues | 92 | 4 (4.4) | p = 0.000 |
Primary tumors of NSCLC | 121 | 62 (51.2) | |
Pathology | Â | Â | Â |
Squamous cell carcinoma | 61 | 31 (50.8) | p = 0.926 |
Adenocarcinoma | 60 | 31 (51.7) | |
Tumor size (T stage) | Â | Â | Â |
T1/ T2 | 98 | 45 (45.0) | p = 0.016 |
T3/ T4 | 23 | 17 (73.3) | |
Lymph node metastasis | Â | Â | Â |
Positive | 60 | 34 (56.7) | p = 0.236 |
Negative | 61 | 28 (45.9) |