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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Redirection of CD4+ and CD8+ T lymphocytes via an anti-CD3 × anti-CD19 bi-specific antibody combined with cytosine arabinoside and the efficient lysis of patient-derived B-ALL cells

Fig. 2

Activation markers expressed by activated T lymphocyte subclones. Expressions of T cell activation markers CD25 (a) and CD69 (b) were significantly increased when T cells were incubated with target cells and diabody. The T cell activation markers increased to higher levels when T cells were incubated with the tumor cells stimulated by Ara-C, then the tumor cells themselves. Expressions of CD25 and CD69 increased equally in both CD4+ and CD8+ T cells, *p < 0.05, **p < 0.01. TC target cells

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