Table 2 Tumor growth in vivo (%)

PBS

87.8 ± 6.8

87.6 ± 9.9

83.5 ± 7.3

83.9 ± 8.9

79.2 ± 9.2

79.6 ± 6.7

85.1 ± 6.1

85.7 ± 8.3

88.3 ± 8.1

88.5 ± 10.4

84.8 ± 5.6

85.1 ± 5.5

T

82.1 ± 5.9

82.8 ± 6.1

80.1 ± 9.4

80.6 ± 5.4

78.2 ± 7.1

78.9 ± 7.8

81.2 ± 5.9

81.0 ± 7.9

80.9 ± 10.9

81.2 ± 7.8

80.5 ± 2.3

80.9 ± 2.0

T + diabody

60.0 ± 7.2

59.8 ± 5.7

60.1 ± 1.6

59.5 ± 5.6

58.8 ± 6.1

58.5 ± 6.5

62.5 ± 2.6

61.9 ± 6.4

62.6 ± 5.7

63.0 ± 3.4

60.8 ± 2.0*

60.5 ± 2.0*

T + ds-diabody

49.5 ± 5.5

48.7 ± 6.2

47.6 ± 3.2

48.1 ± 7.1

46.3 ± 4.6

46.0 ± 5.7

49.1 ± 4.3

49.7 ± 5.1

50.4 ± 7.2

50.7 ± 2.7

48.6 ± 2.3*

48.6 ± 2.6*

T + Ara-C

77.0 ± 8.1

77.8 ± 7.4

67.3 ± 3.3

68.0 ± 4.6

70.1 ± 5.6

69.9 ± 6.9

72.0 ± 6.8

70.8 ± 3.8

75.1 ± 5.3

75.5 ± 5.5

72.3 ± 5.0

72.4 ± 2.5

T + Ara-C + diabody

21.5 ± 3.2

20.8 ± 2.8

15.8 ± 3.1

15.0 ± 3.3

14.3 ± 2.7

13.9 ± 3.7

19.7 ± 2.1

19.1 ± 0.9

17.8 ± 1.1

17.9 ± 2.7

17.8 ± 3.5**

17.3 ± 3.4**

T + Ara-C + ds-diabody

1.3 ± 0.5

1.2 ± 0.4

0.8 ± 0.2

0.7 ± 0.1

0.7 ± 0.2

0.5 ± 0.1

2.5 ± 0.3

2.4 ± 0.4

2.0 ± 1.2

2.1 ± 0.5

1.5 ± 0.8**

1.4 ± 0.9**