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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: All-trans retinoic acid arrests cell cycle in leukemic bone marrow stromal cells by increasing intercellular communication through connexin 43-mediated gap junction

Fig. 2

Effects of ATRA and amphotericin-B pretreatment on Cx43 protein level in leukemic BMSCs. a Cx43 protein (normalized against β-actin) was 1.35 ± 0.17 in healthy controls (N = 10), 0.37 ± 0.02 in leukemic BMSCs (N = 25) treated with DMSO, 1.15 ± 0.03 in leukemic BMSCs exposed to ATRA (10 uM) (N = 25), and 1.07 ± 0.02 in leukemic BMSCs treated with both ATRA and amphotericin-B (N = 25); b relative normalization gray level of Cx43 Western blotting band in health controls, leukemic BMSCs, leukemic BMSCs + ATRA, leukemic BMSCs + ATRA + AB. Data are presented as mean ± SD. Double asterisks indicate P < 0.01

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