Table 1 General characteristics of all patients with MPN (n = 455)

Patients; n (% of total)

454

142

(31.3)

140

(30.8)

113

(24.9)

22

(4.8)

19

(4.2)

18

(4.0)

Male sex; n (%)

232

(51.1)

n = 454

65

(45.8)

n = 142

57

(40.7)

n = 140

76

(67.3)

n =113

11

(50)

n = 22

12

(63.2)

n = 19

11

(61.1)

n = 18

0.0007^#

Age at diagnosis; median, mean (SD)

60

57.7

(15.2)

n = 442

60

59.2

(13.9)

n = 140

54

52.9

(16.5)

n = 137

61.5

60.6

(13.4)

n = 108

63

58.4

(12.6)

n = 21

68

63.9

(17.8)

n = 18

57.5

57

(18.4)

n = 18

0.0008*

Hematocrit^a; median, mean (SD)

42.5

41.9

(10.9)

n = 441

50

49.5

(10.6)

n = 139

41.6

40.4

(7.9)

n = 137

34.6

35.4

(9.6)

n = 108

46

42.7

(10)

n = 21

34.7

34.7

(7.9)

n = 18

42.1

38.9

(7.2)

n = 18

<0.0001*

Platelets^a; median, mean (SD)

516

575.2

(383.7)

n = 441

487

522.2

(269.3)

n = 137

704

789.1

(410.1)

n = 139

376

429.4

(374.4)

n = 109

395.5

446.2

(325.8)

n = 20

279.5

359.3

(271.1)

n = 18

502.5

568.3

(425.3)

n = 18

<0.0001*

LDH^a; median, mean (SD)

307

415.2

(332.5)

n = 409

282

308.3

(121.2)

n = 128

252

314.2

(209.9)

n = 130

462

565.8

(326.8)

n = 101

593.5

717.9

(599.5)

n = 18

670

913.7

(835.8)

n = 15

310

336.8

(162)

n = 17

<0.0001*

Jak2V617F-positive; n (%)

289

(75.5)

n = 383

108

(91.5)

n = 118

71

(61.7)

n = 115

68

(68)

n = 100

18

(100)

n = 18

9

(60)

n = 15

15

(88.2)

n = 17

<0.0001^#

Spleen in cm by ultrasound^a; median, mean (SD)

14.5

15.6

(5.4)

n = 243

13.8

14.6

(3.7)

n = 75

12.5

13.2

(3.4)

n = 61

16.2

16.5

(4.2)

n = 69

23.1

23.9

(12.7)

n = 14

17.4

18.3

(5.3)

n = 14

15.5

16.1

(3.9)

n = 10

<0.0001*