Table 1 Summary of Keap1 amino residuals involved in the activation of Nrf2 signal
From: Emerging roles of Nrf2 signal in non-small cell lung cancer
Author | Interests amino residues | Nrf2 signal activator |
|---|---|---|
2003 Zhang et al. [46] | Cys151, Cys273, Cys288 | Sulforaphane, t-BHQ |
2002 Dinkova-Kostova et al. [47] | Cys257, Cys273, Cys288, Cys297, Cys613 | Dexamethasone, sulforaphane |
2010 McMahon et al. [49] | Cys288, His225, Cys226, Cys613, His129, Lys131, Arg135, Lys150, His154, Cys151 | NO, Zn2+, alkenals |
2014 Wang et al. [48] | Cys151 | Oxaliplatin |