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Fig. 3 | Journal of Hematology & Oncology

Fig. 3

From: Molecular alterations in the TCR signaling pathway in patients with aplastic anemia

Fig. 3

CD3ζ 3′-UTR splicing variant isoforms in AA and HIs. a The WT and AS isoforms could be detected in all of the healthy individuals (lane 1), 64 % of the AA patients contained WT+AS+CD3ζ 3′-UTR (lane 2), 22 % of the AA patients had only the WT+ASCD3ζ 3′-UTR (lanes 4 and 5), and 14 % of the AA patients had only the WT-AS+CD3ζ 3′-UTR (lanes 6 and 7). Lane 3 is a 100 bp DNA ladder; b the expression level of the CD3ζ gene with different CD3ζ 3′-UTR splicing variant isoforms in SAA

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