Fig. 1

The induction of HOTAIRM1 upon ATRA treatment requires the intermediate protein synthesis. a The expression levels of two HOTAIRM1 variants at different time points following 1 μM ATRA treatment in NB4 cells. b The expression levels of two HOTAIRM1 variants in NB4 cells before and after ATRA treatment (1 μM) for 8 h, with or without 30 min CHX pretreatment (100 μg/mL). The relative expression level was calculated relative to that of variant 1 at 0 h. An average of two control genes (GAPDH and ACTB) was used for normalization. The data represent the mean of three replicates ± SD. *p < 0.05; **p < 0.01