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Table 4 Causes of death according to donor HLA matching

From: The impact of HLA-matching on reduced intensity conditioning regimen unrelated donor allogeneic stem cell transplantation for acute myeloid leukemia in patients above 50 years—a report from the EBMT acute leukemia working party

  HLA 10/10 HLA 9/10 HLA 8/10
Relapse 552 (47.5 %) 173 (43.4 %) 21 (36.2 %)
Infection 249 (21.3 %) 100 (25.1 %) 21 (36.2 %)
GVHD 202 (17.3 %) 80 (20.1 %) 10 (17.2 %)
Graft failure/rejection 11 (0.9 %) 1 (0.3 %) 0
Cardiac toxicity 8 (0.7 %) 4 (1 %) 1 (1.7 %)
Haemorhage 14 (1.2 %) 5 (1.3 %) 1 (1.7 %)
VOD 12 (1 %) 8 (2 %) 0
Idiopathic pneumonia 25 (2.1 %) 9 (2.3 %) 0
Second malignancy 24 (2.1 %) 5 (1.3 %) 0
Other SCT-related 70 (6 %) 14 (3.5 %) 4 (6.9 %)
  1. GVHD graft-versus-host disease, SCT stem cell transplantation, VOD veno-occlusive disease