Table 4 Multivariate analysis for patients with AML in primary relapse according to HLA mismatch

 UD 10/10

0.75 (0.63–0.90)

<0.01

 UD 9/10

0.77 (0.57–1.05)

0.10

 Age^a

0.99 (0.99–1.00)

0.02

 Time from dx to Tx >9 mo

0.62 (0.52–0.72)

<0.01

 Female donor to male recipient

0.91 (0.74–1.11)

0.34

 sAML

0.99 (0.79–1.23)

0.92

 previous auto-HSCT

1.22 (0.86–1.73)

0.26

 Positive recipient CMV serology

0.96 (0.80–1.15)

0.68

 Positive donor CMV serology

1.03 (0.86–1.22)

0.77

 RIC

1.21 (1.02–1.42)

0.03

 UD 10/10

0.97 (0.74–1.29)

0.86

 UD 9/10

1.32 (0.87–2.00)

0.19

 Age^a

1.02 (1.01–1.03)

<0.01

 Time from dx to Tx >9 mo

0.81 (0.62–1.04)

0.10

 Female donor to male recipient

0.86 (0.61–1.20)

0.38

 sAML

1.40 (1.04–1.90)

0.03

 previous auto-HSCT

1.50 (0.92–2.45)

0.10

 Positive recipient CMV serology

0.96 (0.72–1.28)

0.80

 Positive donor CMV serology

0.98 (0.75–1.29)

0.90

 RIC

0.96 (0.74–1.25)

0.78

 UD 10/10

0.81 (0.70–0.94)

0.01

 UD 9/10

0.92 (0.72–1.18)

0.53

 Age^a

1.00 (0.99–1.00)

0.82

 Time from dx to Tx >9 mo

0.67 (0.58–0.76)

<0.01

 Female donor to male recipient

0.89 (0.75–1.07)

0.21

 sAML

1.11 (0.93–1.33)

0.24

 previous auto-HSCT

1.30 (0.98–1.72)

0.07

 Positive recipient CMV serology

0.97 (0.83–1.13)

0.67

 Positive donor CMV serology

1.01 (0.88–1.17)

0.86

 RIC

1.13 (0.98–1.30)

0.08

 UD 10/10

0.87 (0.74–1.01)

0.07

 UD 9/10

1.00 (0.78–1.29)

0.99

 Age^a

1.00 (1.00–1.01)

0.36

 Time from dx to Tx >9 mo

0.70 (0.61–0.81)

<0.01

 Female donor to male recipient

0.85 (0.71–1.03)

0.09

 sAML

1.10 (0.91–1.32)

0.31

 previous auto-HSCT

1.25 (0.93–1.69)

0.14

 Positive recipient CMV serology

0.95 (0.81–1.12)

0.56

 Positive donor CMV serology

0.99 (0.85–1.16)

0.94

 RIC

1.01 (0.88–1.17)

0.86