Fig. 5
The positive regulatory loop of Sox2–Wnt/β-catenin–MYC in RR cells. a qRT-PCR assay was performed to analyze the relative mRNA levels of WNT2B, CTNNB1, MYC, and BCL9 in RR cells derived from SupM2 and Karpas 299 cells with scr siRNA or Sox2 siRNA transfection at 48 h. b The protein levels of Sox2, p-MYCS62, and MYC in RR cells with scr siRNA or Sox2 siRNA transfection at 48 h. c The cell models of RR and RU cells