Fig. 3From: TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemiaTIGAR regulated the glycolysis through PFKFB3 in leukemia cells. a, b TIGAR knockdown reduced the GSH level and increased the ROS level in NB-4 cells (a) and HL-60 cells (b). c TIGAR overexpression increased the GSH level and reduced the ROS level in K562 cellsBack to article page