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Table 1 Summary of circRNAs in cancer

From: Circular RNAs in cancer: an emerging key player

Cancer name CircRNA name Expression level Scope Sample Intersection molecules and/or pathway References
Bladder carcinoma circTCF25 Up Bladder carcinoma vs normal Tissues (n = 40) miR-103a-3p,miR-107; circTCF25-miR-103a-3p/miR-107-CDK6 Zhong et al. [28]
cSCC hsa_circ_0035381 Up cSCC vs normal Tissues (n = 12) hsa-miR-124-5p,hsa-miR-9-5p Sand et al. [32]
hsa_circ_0022383 Down hsa-miR-124-5p
ESCC cir-ITCH Down ESCC vs normal Tissues (n = 684) miR-7, miR-17, and miR-214;Wnt/β-catenin pathway Li et al. [34]
Gastric cancer has_circ_002059 Down Gastric cancer vs normal Tissues (n = 101) Li et al. [23]
Plasma (n = 36)
CRC hsa_circ_001988 Down CRC vs normal Tissues (n = 31) Wang et al. [24]
cir-ITCH Down CRC vs normal Tissues (n = 45) Wnt/β-catenin pathway Huang et al. [25]
HCC hsa_circ_0001649 Down HCC vs normal Tissues (n = 89) Qin et al. [26]
LSCC hsa_circ_104912 Down LSCC vs normal Tissues (n = 52) Xuan et al. [27]
hsa_circ_100855 Up
APL f-circRNA f-circRNA-expressing vas normal Cells PI3K and MAPK signal transduction pathways Guarnerio et al. [29]
  1. Notes: Up upregulated, down downregulated
  2. Abbreviations: circRNAs circular RNAs, cSCC cutaneous squamous cell carcinoma, ESCC esophageal squamous cell carcinoma, CRC colorectal cancer, HCC hepatocellular carcinoma, LSCC laryngeal squamous cell cancer, APL acute promyelocytic leukemia