Fig. 1
DOT1L protein expression in human ovarian tissues and Kaplan-Meier plots. a Immunohistochemical staining of DOT1L protein in human ovarian tissues. A brown color in cancer cells is considered as a positive staining. Negative control without first antibody is performed in the normal ovarian tissue. Representative images of DOT1L expression in normal ovarian tissues and benign, borderline, and malignant ovarian tumors are shown. Original magnification ×100 and ×400. Scale bar 100 and 25 μm, respectively. b The case rate of DOT1L high and low expression. For comparison between two groups, χ 2 test was applied. c Overall survival (OS) rate in patients with high DOT1L expression was significantly lower than in patients with no or low DOT1L expression. d Progression-free survival (PFS) rate in patients with high DOT1L expression was significantly lower than in patients with no or low DOT1L expression