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Table 1 Classification of single-cell analysis methods

From: Studying hematopoiesis using single-cell technologies

Method Amplification Coverage References
Genomics
 MDA MDA High coverage [30]
 MALBAC MALBAC High coverage [31]
Transcriptomics
 Single-cell qPCR Multiplexed PCR Target gene [16]
 Tang-seq PolyA tailing + second-strand synthesis Full-length mRNAs [34]
 CEL-seq In vitro transcription 3′ End of mRNA [21]
 Smart-seq Template switching Full-length mRNAs [36]
 Cyto-seq Multiplexed PCR 3′ End of mRNA [23]
 Drop-seq Template switching 3′ End of mRNA [24]
 inDrop In vitro transcription 3′ End of mRNA [25]
Proteomics
 Mass cytometry NA Target protein [55]
Epigenomics
 scATAC-seq Adaptor PCR Accessible DNA regions [64]
 scRRBS Adaptor PCR 1.5 million CpG sites [59]
 scHi-C Adaptor PCR NA [63]
 scChIP-seq Adaptor PCR About 1000 peaks [62]
  1. NA not applicable