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Table 2 Trabectedin plus rucaparib combination study: combination index according to Chou and Talalay

From: Activity of trabectedin and the PARP inhibitor rucaparib in soft-tissue sarcomas

Cell lines Combination index Comments
IB114 0.64 Synergistic
IB115 0.75 Synergistic
IB111 0.71 Synergistic
IB133 1.17 Antagonist
IB134 1.02 Additive
IB136 1.18 Antagonist
IB112 0.99 Additive
IB128 0.92 Additive
93T449 0.86 Synergistic