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Fig. 3 | Journal of Hematology & Oncology

Fig. 3

From: Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia

Fig. 3

Expression of Blimp-1 in CD8+ T cells associates with increased differentiation of terminal differentiated effector T cells in AML. Distribution of TN, TCM, TEM, and TEMRA within Blimp-1− vs. Blimp-1+ T cells from AML patients (n = 14) are assessed by flow cytometry. Both CD4+ and CD8+ T cells are evaluated. Representative flow data (a) and plots (b) of percentage of each T cell differentiation subset among Blimp-1− vs. Blimp-1+ T cells are shown. P values were obtained by paired t test and Wilcoxon signed-rank test.

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