Fig. 5

miR-330-3p induces tumorigenesis in a xenograft mouse model. a, b H460 and H1975 cells stably transfected with NC-LV, OE-miR-330-3p-LV, or anti-miR-330-3p-LV were injected subcutaneously into nude mice. Four weeks after the injection, mice were photographed and killed. Tumor growth curves were obtained. All data were presented as mean of three independent experiments ± SD, *P < 0.05, **P < 0.01, #P < 0.001, one-way ANOVA test. c Representative bioluminescence images of tumor burden in the mice that received subcutaneous injection of indicated cells. d Survival curves represent the duration from injection until 4 weeks when mice were killed