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Table 1 Immune profile of AML patients’ BM mononuclear cells

From: An improved pre-clinical patient-derived liquid xenograft mouse model for acute myeloid leukemia

   % Relative to human CD45
Donor No. of mononuclear cellsa injected per NSG pupb CD45loCD34+ CD45loCD34+CD33+CD117+ CD45loCD34 CD45loCD34CD33+CD117+
Leu 14 6.5 × 105 61.4 10.7 35.7 0.1
Leu 29 2.9 × 105 3.1 0.0 8.6 0.0
Leu 32 8.7 × 104 53.0 0.0 27.5 0.0
Leu 33 2.6 × 105 1.1 0.0 15.5 0.0
BMI 1690 5.0 × 105 56.1 1.2 32.7 5.5
BMI 1786 7.9 × 105 72.0 1.0 19.3 0.0
BMI 1808 6.7 × 105 34.7 3.6 50.3 14.1
  1. aRefers to CD3-depleted mononuclear cells
  2. bRefers to 1–3-day-old NSG newborn