Fig. 4
From: The role of B cell antigen receptors in mantle cell lymphoma
Four potential ways of B cell receptor activation in the pathogenesis of mantle cell lymphoma. a Antigen binding to the CDR3 of the BCR. b Antigen-independent autologous signaling of the BCR. c Superantigen-triggered BCR activation. d Superantigens facilitating BCR activation by classical may be low affinity antigen binding or CD79 aberrations