|
Clinico pathologic feature
|
GD2+ (%)
|
GD2− (%)
|
P valuea
|
|---|
|
Age (year)
|
|
Median (range)
|
52.7 ± 13.5
|
51.1 ± 15.2
|
0.348
|
|
Gender n (%)
|
|
Male
|
69 (48.6)
|
74 (50.7)
|
0.722
|
|
Female
|
73 (51.4)
|
72 (49.3)
|
|
Ulceration n (%)
|
|
Yes
|
82 (57.7)
|
84 (57.5)
|
0.971
|
|
No
|
60 (42.3)
|
62 (42.5)
|
|
Thickness
|
|
Median (range)
|
3.5 (0.5,20.0)
|
3.7 (0.5,19.5)
|
0.581
|
|
TNM stage n (%)
|
|
I (16)
|
5 (3.5)
|
11 (7.5)
|
0.003
|
|
II (109)
|
41 (28.9)
|
68 (46.6)
|
|
III (92)
|
55 (38.7)
|
37 (25.3)
|
|
IV (71)
|
41 (28.9)
|
30 (20.5)
|
|
Metastasis
|
|
Yes
|
96 (67.6)
|
67 (45.9)
|
< 0.0001
|
|
No
|
46 (32.4)
|
79 (54.1)
|
|
Primary site
|
|
Acral (134)
|
67 (47.2)
|
67 (45.9)
|
0.017
|
|
Mucosal (71)
|
40 (28.2)
|
31 (21.2)
|
|
CSD (14)
|
2 (1.4)
|
12 (8.2)
|
|
Non-CSD (27)
|
9 (6.3)
|
18 (12.3)
|
|
Unknown primary (42)
|
24 (16.9)
|
18 (12.3)
|
|
Survival (months)
|
|
Median (95% CI)
|
31 (34.1,60.1)
|
47.1 (21.3,40.7)
|
< 0.0001
|
- aFor evaluation of age, the two independent sample t test or one-way ANOVA was used. For evaluation of gender, ulceration, and TNM stage, the chi-square tests or Fisher’s exact tests were used. For evaluation of thickness, Mann-Whitney U tests were used. For evaluation of OS time, Log-rank tests were used
