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Table 1 Correlation of SAE2 expression with clinicopathological parameters in patients with LADC

From: The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells

 

Expression of SAE2

 

P value

 

Parameter

High (n = 302)

Low (n = 70)

Univariate

Multivariate

Gender

 Male (n = 292)

243

49

0.0549†

0.107

 Female (n = 80)

59

21

  

Cigarette smoking

 Smoker (n = 266)

227

39

0.0012†

0.0025

 Non-smoker (n = 106)

75

31

  

Stage

 I (n = 83)

65

18

0.042‡

0.091

 II (n = 109)

81

28

  

 IIIa (n = 180)

156

24

  

Cell differentiation

 Well (n = 56)

42

14

0.205‡

0.41

 Moderate (n = 211)

172

39

  

 Poor (n = 105)

88

17

  

Lymphovascular invasion

 Positive (n = 278)

244

34

< 0.001†

0.0021

 Negative (n = 94)

58

36

  
  1. †Two-sided P value determined by χ2 test
  2. ‡Two-sided P value determined by χ2 test for trend