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Fig. 3 | Journal of Hematology & Oncology

Fig. 3

From: The chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis

Fig. 3

Baf200 is required for the FL HSC maintenance. a Scheme of competitive FL transplantation assay. b Representative FACS profiles showing the frequency of T cells (CD3+), B cells (B220+), neutrophils (Gr1highCD11b+) in the peripheral blood, and LSK (LinSca1+c-Kit+) cells in the BM from recipient mice 16 weeks after transplantation (left) and the graph showing the relative ratios of CD45.2 versus CD45.1 of the indicated cell types in recipient mice 16 weeks after transplantation (right) (n = 5 per genotype). c Scheme of competitive FL transplantation assay in Mx1-Cre mouse strain. d Percentage of donor-derived T cells (left), B cells (middle), and neutrophils (right) in the peripheral blood from recipient mice assessed at different time points (n = 5 per genotype for each subset). Data are shown as means ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001

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