Fig. 1
From: Circular RNAs: a new frontier for cancer diagnosis and therapy
Possible approaches to target circRNAs. a siRNA-mediated circRNA-specific silencing. b ASO-mediated circRNA-specific silencing. c knockdown or knockout circRNA using CRISPR/Cas9. d Blockade of the combination between circRNA and miRNA or RBP by saturating the binding sites conserved on circRNA. e Reintroduction of circRNAs that are miRNA or RBP sponges