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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: The proto-oncogene Mer tyrosine kinase is a novel therapeutic target in mantle cell lymphoma

Fig. 1

MerTK was ectopically expressed in MCL cell lines and patients’ samples. a MerTK expression in MCL cell lines and normal B cells was detected by western blot. Actin is shown as a loading control. JVM-2 and JVM-13 expressed MerTK at bands 180 and 110 kD, whereas Z-138 and Mino cells expressed MerTK at bands 180 kD. b Representative pictures of immunohistochemistry staining for MerTK in sections of paraffin-embedded MCL tissues. c, d Kaplan–Meier curves for OS (c) and PFS (d) of 55 MCL patients receiving R-CHOP-like regimens according to MerTK expression. e MerTK was located in cell membrane in Z-138, Mino, and JVM-2 cells. MerTK expression (red) was detected by immunofluorescence

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