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Table 1 Patient characteristics

From: Multi-center phase II trial of bortezomib and rituximab maintenance combination therapy in patients with mantle cell lymphoma after consolidative autologous stem cell transplantation

Characteristics

n (%)

Age at initial treatment, years; median (range)

59 (45ā€“66)

Gender

ā€ƒFemale

1 (4)

ā€ƒMale

22 (96)

Disease stage at diagnosis

ā€ƒI

0 (0)

ā€ƒII

2 (9)

ā€ƒIII

4 (17)

ā€ƒIV

16 (70)

ā€ƒUnknown

1 (4)

Extranodal disease at diagnosis

ā€ƒNo

7 (30)

ā€ƒYes

16 (70)

Time from auto-HCT to initial maintenance treatment (months); median (range)

3.5 (2.3ā€“5.8)

MIPI at diagnosis

ā€ƒLow

10

ā€ƒIntermediate

12

ā€ƒHigh

0

ā€ƒUnknown

1

Conditioning regimens for prior auto-HCT

ā€ƒBEAM

18 (78)

ā€ƒCBV

5 (22)

Induction regimens

ā€ƒR-bendamustine

3

ā€ƒR-HCVAD/MTX/ARA-C

8

ā€ƒNORDIC

4

ā€ƒRCHOP

3

ā€ƒVR-CAP

2

ā€ƒIbrutinib

1

Relapsed

ā€ƒRCHOP followed by R-HCVAD/MTX/ARA-C

1

ā€ƒRCHOP followed by R-bendamustine

1

  1. Abbreviations: BEAM carmustine, cytarabine, etoposide, and melphalan; CBV cyclophosphamide, carmustine, and etoposide; R, rituximab; MTX methotrexate; Ara-C cytarabine; NORDIC maximum-strength rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone alternating with rituximab, high-dose cytarabine; R-HCVAD rituximab, cyclophosphamide, vincristine, doxorubicin, dexamethasone; RCHOP rituximab, cyclophosphamide, doxorubicin vincristine, and prednisone; VR-CAP bortezomib, rituximab, cyclophosphamide, doxorubicin, prednisone