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Table 1 Population characteristics

From: Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation: an EBMT-Eurocord study of acute leukemia patients conditioned with thiotepa, busulfan, and fludarabine

 

NTD-Haplo (n = 186)

SUCBT (n = 147)

p value

Follow-up, months median (range)

22.07 (0–96.3)

24.42 (0–83.1)

 

HSCT year, median (range)

2014 (2008–2015)

2011 (2007–2015)

< 0.001

Age, years. median (range)

44.3 (18.5–66.1)

42.6 (18–67.9)

0.046

Recipient sex

 Male

85 (45.7%)

65 (44.2%)

0.787

 Female

101 (54.3%)

82 (55.8%)

 

 Missing

0

6

 

Karnofsky performance status

 < 90

21 (12.5%)

15 (15.31%)

0.519

 ≥ 90

147 (87.5%)

83 (84.69%)

 

 Missing

18

49

 

Interval from diagnosis to HSCT, months, median (range)

6.6 (2.1–189.6)

6 (3–214.2)

0.097

Disease status at HSCT

 CR1

130 (69.9%)

113 (76.9%)

0.154

 CR2

56 (30.1%)

34 (23.1%)

 

MRC risk classification

 Good

16 (8.6%)

13 (8.8%)

0.762

 Intermediate

67 (36.0%)

60 (40.8%)

 

 Poor

19 (10.2%)

16 (10.9%)

 

 Missing

84 (45.2%)

58 (39.5%)

 

Female donor to male recipient

 No

143 (76.9%)

108 (76.6%)

0.952

 Yes

43 (23.1%)

33 (23.4%)

 

Recipient CMV serostatus

  

< 0.001

 Negative

35 (19.1%)

29 (25.9%)

 

 Positive

148 (80.9%)

83 (74.1%)

 

 Missing

3

35

 

In-vivo T cell depletion (ATG)

 No

131 (71.2%)

13 (9.0%)

< 0.001

 Yes

53 (28.8%)

131 (91.0%)

 

 Missing

2

3

 
  1. NTD-Haplo Non-T cell depleted haploidentical transplantation, SUCBT single umbilical cord blood transplantation, HSCT hematopoietic stem cell transplantation, CR complete remission, MRC Medical Research Council, CMV cytomegalovirus, ATG antithymocyte globulin