Potential application | LncRNA | Expression | Clinical significance | Sample size | Ref. |
---|---|---|---|---|---|
Diagnostic biomarker | POU3F3 | Up | – | Plasma of 147 ESCC patients and 123 healthy donors | [148] |
 | Linc00152, CFLAR-AS1, and POU3F3 | Up | Poor post-surgery prognosis | Plasma of 205 ESCC patients, 82 esophagus dysplasia patients and 210 healthy donors | [149] |
 | MIR31HG | Down | TNM stage, lymphatic metastasis, and poorer OS | Plasma of 205 ESCC patients and 39 healthy donors | [153] |
Prognostic biomarker | ATB | Up | TNM stage and poor DFS | 150 paired ESCC tissues | [51] |
 | XIST | Up | Shorter DFS and OS | 127 paired ESCC tissues | [74] |
 | AK001796 | Up | TNM stages, lymph node metastasis, and shorter OS | 50 paired ESCC tissues | [93] |
 | ZEB1-AS1 | Up | Tumor grade, depth of invasion, lymph node metastasis, and shorter DFS and OS | 87 paired ESCC tissues | [145] |
 | MALAT1 | Up | Lymphatic invasion, distant metastasis, tumor differentiation, and shorter OS | 106 paired ESCC tissues | [147] |
 | PCAT-1 | Up | Lymph node metastasis, TNM stage, and poorer OS | 130 paired ESCC tissues | [161] |
 | NKILA | Down | Tumor size, TNM stage, poor DFS, and OS | 137 paired ESCC tissues | [162] |
 | SPRY4-IT1 | Up | Clinical stage and shorter OS | 92 paired ESCC tissues | [163] |
 | ZFAS1 | Up | Poor OS | 50 paired ESCC tissues | [164] |