Skip to main content

Table 6 The list of significantly correlated DNA methylation and the expression of the intronic and intergenic methylated lncRNAs (n = 5) from DUX4 BCP-ALL subtypes

From: Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia

DM lncRNAs Absolute fold change Methylation value Pearson correlation rate P value Epi-markers Biotype
RP11-134O21.1 2.54 − 1.56 − 0.63 1.9E−010 Enhancer Intron
RP11-398B16.2 2.08 − 1.85 − 0.47 0.0007 Insulator
RP11-689B22.2 1.52 − 3.37 − 0.47 0.008 Enhancer
CTC-458I2.2 − 1.16 3.38 − 0.42 0.0001 Enhancer
LINC00880 − 1.45 2.23 − 0.25 0.02 Enhancer Intergenic
  1. The significance is calculated based on Pearson correlation rate and two-tailed P value ≤ 0.05. The lncRNAs are promoter differentially methylated and differentially expressed in their corresponding subtypes. These lncRNAs are with enhancer and insulator epigenetic markers. DM, differentially methylated