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Table 3 Multivariate analysis results

From: Allogeneic hematopoietic cell transplantation provides effective salvage despite refractory disease or failed prior autologous transplant in angioimmunoblastic T-cell lymphoma: a CIBMTR analysis

  Number RR 95% CI lower limit 95% CI upper limit P-value Overall p value
Chronic GVHD
 ATG/alemtuzumab
  No 174 1     0.02
  Yes 55 0.58 0.36 0.93 0.02  
Progression/Relapse
 No significant covariates
Non-relapse mortality
 No significant covariates
Progression-free survival
 Disease status
  CR 108 1     0.03
  PR 90 1.13 0.76 1.66 0.54  
  Chemoresistant 38 1.73 1.08 2.77 0.02  
  Missing/Untreated 13 0.43 0.15 1.20 0.11  
Overall survival
 Karnofsky performance score (≤ 6 months)a
  ≥ 90% 119 1     0.002
  < 90% 113 3.46 1.74 6.87 0.0004  
  Missing 17 1.95 0.54 6.98 0.31  
 Karnofsky performance score (> 6 months)a
  ≥ 90% 106 1     0.28
  < 90% 80 0.66 0.39 1.12 0.12  
  Missing 14 0.73 0.29 1.86 0.51  
  1. GVHD graft-versus-host disease, CI confidence interval, ATG anti-thymocyte globulin, CR complete remission, PR partial remission, RR relative risk
  2. Variables tested in the Multivariate analysis are listed in Additional file 1 Table S2
  3. a6-months was chosen as cut-off based on the maximum likelihood value in the Cox model
  4. p-value <0.05 is considered significant