Fig. 6

miR-195-5p suppresses tumor growth and M2-likeTAM infiltration in vivo. a Immunohistochemistry of tumor tissues treated with or without miR-195-5p. b Western blots of E-cadherin, Vimentin, NOTCH2, Ad-NOTCH2, GATA3 and IL-4 in the tumors. GAPDH was used as a loading control. c Representative photomicrographs and quantifications (d) of CTCs captured from blood of mice. Assays were performed in triplicates. Mean ± SD is shown. Statistical analysis was conducted using Student’s t test. f Interaction between CRC EMT and M2-like TAMs in TME