Fig. 1

Genomic landscape of Chinese LUSC and its correlations with TMB, PD-L1 expression, or immune cells infiltration. a The identified somatic mutations of all cases. b The identified copy number variations of all samples. c–p Association between frequent alterations including TP53 (c), KMT2C (d), NFE2L2 (e), KEAP1 (f), CDKN2A (j), PTEN (k), FBXW7 (l) and PIK3CA (m) mutations, FGFR1 (g), PIK3CA (h), EGFR (i), CCND1 (n) and SOX2 (p) amplification, loss of CDKN2A (o), and TMB. q–r Association between frequent somatic mutations and PD-L1 expression (q), CD8+ TIL expression (r). s–t Association between frequent copy number variations and PD-L1 expression (s), CD8+ TIL expression (t)