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Table 3 The application of TEXs in clinical diagnosis

From: Tumor-derived exosomes, myeloid-derived suppressor cells, and tumor microenvironment

TEX-molecule Type of cancer TEXs source Application Refs
CD63 Melanoma Plasma Diagnosis and prognosis [129]
Caveolin-1
GPC1 Pancreatic cancer Serum Early diagnosis [130]
miR-373 Triple-negative breast cancer Serum Diagnosis and prognosis [133]
miR-1290 Prostate cancer Plasma Therapy monitoring [134]
miR-375
miR-19a Colorectal cancer Serum Prognosis [134]
let-7a AML Serum Early diagnosis [135]
miR-99b
miR-146a
miR-155
miR-191
miR-1246
miR-141 Prostate cancer Serum Early diagnosis [136]
lncRNA CRNDE-p Colorectal cancer Serum Diagnosis and prognosis [137]
miR-217
lncRNA HOTAIR Cervical cancer Cervicovaginal Lavage Samples Early diagnosis [138]
lncRNA MALAT1
lncRNA MEG3
miR-21 Lung cancer Serum Early diagnosis [139]
lncRNA HOTAIR
lncRNA ZFAS1 Gastric cancer Serum Early diagnosis [140]
circ-KLDHC10 Colorectal cancer Serum Early diagnosis [37]
  1. Implies the clinical application of TEX-molecules as biomarkers in informing the presence of malignant disease and tumor burden