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Table 2 Univariate and multivariate analysis of prognostic factors for overall survival in LUAD patients

From: MAGE-A1 in lung adenocarcinoma as a promising target of chimeric antigen receptor T cells

  Univariate analysis Multivariate analysis
HR p value 95% CI HR p value 95% CI
MAGE-A1 expression
 High versus low 1.78 0.022* 1.09–2.93 1.58 0.087 0.93–2.68
Gender
 Male versus female 1.38 0.183 0.86–2.20    
Age
 ≥ 60 years versus < 60 years 0.96 0.861 0.59–1.55    
Tumor diameter
 ≥ 3 cm versus < 3 cm 1.54 0.090 0.93–2.55    
Pathological grade
 Grade I–II versus grade III 0.88 0.633 0.53–1.47    
Lymph node metastasis
 Positive versus negative 2.47 0.001* 1.49–4.09 1.02 0.950 0.44–2.42
T status
 T1–T2 versus T3–T4 0.71 0.196 0.42–1.20    
N status
 Positive versus negative 2.11 0.002* 1.31–3.41 1.42 0.265 0.77–2.65
M status
 Positive versus negative 1.09 0.930 0.15–7.90    
TNM stage
 Stage I–II versus stage III–IV 0.36 0.001* 0.21–0.59 0.45 0.029* 0.22–0.92
  1. HR hazard ration, CI confidence interval, LUAD lung adenocarcinoma
  2. *p < 0.05