From: LSD1/KDM1A inhibitors in clinical trials: advances and prospects
 | Cmax (ng/mL) | Tmax (h) | AUC(0-last) (ng*h/mL or ng*h/g) | AUC(0-inf) (hr*ng/mL or hr*ng/g) | DNAUC(0-last) (ng*h/mL/mg/k g) | T1/2 (h) | AUC_%Extrap_pred (%) |
---|---|---|---|---|---|---|---|
Blood | 720 | 0.25 | 852.7 | 903.2 | 171 | 1.9 | 5.6 |
Tumor | 354.7 | 0.5 | 2321.6 | 2693.0 | 464 | 8.4 | 13.8 |