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Fig. 6 | Journal of Hematology & Oncology

Fig. 6

From: Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3β signalling pathway in renal cell carcinoma

Fig. 6

AGK stimulates the PI3K/AKT signalling pathway. a KEGG analysis was conducted to identify the pathways activated by AGK overexpression in RCC. b MTT assay, c colony formation assay and d flow cytometric analysis of the proliferation of the indicated RCC cells in the presence or absence of the PI3K inhibitor LY294002. Cell migration and invasion were measured by wound-healing (e) and Transwell assays (f) in the presence or absence of LY294002. g Western blotting analysis of the expression of p-AKT, p-PI3K, total AKT and total PI3K. GAPDH served as the loading control

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Journal of Hematology & Oncology

ISSN: 1756-8722

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