Table 3 Cellular distribution of the major human FcγRs [29]
From: How to select IgG subclasses in developing anti-tumor therapeutic antibodies
FcγR | Cellular distribution |
|---|---|
FcγRI | Monocytes, macrophages, activated neutrophils, DCs |
FcγRIIa | Monocytes, macrophages, neutrophils, DCs |
FcγRIIb | B cells, monocytes, macrophages, DCs, mast cells |
FcγRIIIa | NK cells, monocytes, macrophages |