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Table 2 Univariable analysis of transplants outcomes according to donor type

From: Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia: a comparative study of the ALWP EBMT

Outcome*

MSD

MUD

Haplo

p

Acute GvHD, % (95% CI)

 Grades II–IV

17 (12–23)

28 (22–34)

26 (23–29)

0.03

 Grades III–IV

6 (4–10)

8 (5–11)

9 (7–12)

0.2

Chronic GvHD, % (95% CI)

 Overall

34 (26–41)

32 (25–39)

30 (26–33)

0.3

 Extensive type

14 (9–20)

18 (13–25)

10 (8–13)

0.003

NRM, % (95% CI)

10 (6–15))

14 (9–19)

23 (20–26)

< 0.001

RI, % (95% CI)

33 (26–40)

25 (19–31)

23 (20–26)

0.02

LFS, % (95% CI)

57 (49–65)

62 (55–69)

54 (51–58)

0.2

OS, % (95% CI)

64 (56–72)

68 (62–75)

61 (58–65)

0.1

GRFS, % (95% CI)

45 (37–53)

42 (35–50)

46 (42–50)

0.9

  1. *Acute GvHD: 100-day cumulative incidence; cGvHD, NRM, and RI: cumulative incidence at 2 years; DFS, OS, and GRFS: survival probability at 2 years
  2. GvHD graft-versus-host disease, CI confidence interval, NRM non-relapse mortality, RI relapse incidence, LFS leukemia-free survival, OS overall survival, GRFS graft-versus-host disease and relapse-free survival