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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma

Fig. 2

Methylation-expression correlation in the t(4;14) and t(11;14) subgroups. DNA methylation level (horizontal; median values) at DMRs vs. expression (vertical; log2 values) of nearest genes were plotted for promoter (a) and gene body (b) in t(4;14) and t(11;14) (d, e) subgroups compared to the control. DMR methylation level vs. expression (based on correlation r2>0.2, excluding control) of selected biologically relevant GEMs in MM were represented as heat maps for the t(4;14) (c) and t(11;14) subgroup (f).

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