Fig. 2
From: Roles of METTL3 in cancer: mechanisms and therapeutic targeting
Regulation on the expression of METTL3 and its function on m6A deposition. a Multi-level regulation of METTL3. b Sequester or recruitment of METTL3 by RNA binding proteins (RBP). c Histone H3K36me3 directed deposition of m6A via recruiting of METTL14 and METTL3. d Recruitment of METTL3 by transcriptional factors (TF). e METTL3 guided by long non-coding RNAs (lncRNA). M3, METTL3; M14, METTL14