Table 2 Representative potential biomarkers identified by RNA-seq in cancer
From: RNA sequencing: new technologies and applications in cancer research
Cancer type | Biomarker name | Biomarker type | Up/Down | Value | References |
|---|---|---|---|---|---|
Liver cancer | tRNA-ValTAC-3/tRNA-GlyTCC-5/tRNA-ValAAC-5/tRNA-GluCTC-5 | tsRNA | Up | Diagnostic | [92] |
| Â | ACVR2B-AS1 | LncRNA | Up | Prognostic/therapeutic target | [93] |
Lung cancer | LINC01537 | LncRNA | Down | Prognostic/therapeutic target | [94] |
circFARSA | CircRNA | Up | Noninvasive biomarker | [95] | |
LINC01123 | LncRNA | Up | Prognostic/therapeutic target | [96] | |
Gastric cancer | CTD2510F5.4 | LncRNA | Up | Diagnostic/prognostic | [97] |
MEF2C-AS1/FENDRR | LncRNA | Down | Diagnostic/prognostic | [98] | |
Prostate cancer | PSLNR | LncRNA | Down | Diagnostic/therapeutic target | [99] |
Colorectal cancer | RAMS11 | LncRNA | Up | Therapeutic target | [100] |
CRCAL-1/CRCAL-2 /CRCAL-3/ CRCAL-4 | LncRNA | Up | Therapeutic target | [101] | |
Colon cancer | AFAP1-AS1 | LncRNA | Up | Prognostic/ therapeutic target | [102] |
Head and neck squamous cell carcinoma | LINC00460 | LncRNA | Up | Prognostic | [103] |
HCG22 | LncRNA | Down | Prognostic | [104] | |
HOXA11-AS/LINC00964/MALAT1 | LncRNA | Up | Diagnostic | [105] | |
Clear cell renal cell carcinomas | SLINKY | LncRNA | Up | Prognostic | [106] |
Leukemia | LUCAT1 | LncRNA | Up | Therapeutic target | [107] |
circ-HIPK2 | CircRNA | Down | Diagnostic/prognostic | [108] |