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Table 2 Transplant characteristics

From: Outcome of haploidentical versus matched sibling donors in hematopoietic stem cell transplantation for adult patients with acute lymphoblastic leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Clinical parameter MSD (n = 1891) Haplo (n = 413) p
Conditioning intensity    
Myeloablative conditioning, n (%) 1574 (83.2%) 281 (68%) < 0.0001
Reduced intensity conditioning, n (%) 317 (16.8%) 132 (32%)  
TBI    
CT 663 (35.1%) 237 (57.4%) < 0.0001
TBI 1228 (64.9%) 176 (42.6%)  
Graft source    
Bone marrow 351 (18.6%) 191 (46.2%) < 0.0001
Peripheral blood 1540 (81.4%) 222 (53.8%)  
PTCy    
No PTCy 1812 (95.8%) 30 (7.3%) < 0.0001
PTCy 79 (4.2%) 383 (92.7%)  
In vivo T-cell depletion    
No ATG 1537 (81.3%) 352 (85.2%) 0.058
ATG 354 (18.7%) 61 (14.8%)  
  1. MSD: matched sibling donor, Haplo: haploidentical transplantation, MAC: myeloablative conditioning, RIC: reduced intensity conditioning, TBI: total body irradiation; BM: bone marrow; PB: mobilized peripheral blood stem cells; PTCy: post-transplantation cyclophosphamide; ATG: anti-thymocyte globulin; MAC: myeloablative conditioning; TBI: total body irradiation; CT: chemotherapy; RIC: reduced intensity conditioning