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Table 1 Expression and clinical significance of UBE2F and UBE2M in tumors

From: Targeting neddylation E2s: a novel therapeutic strategy in cancer

  Cancer Expression Function
UBE2M Osteosarcoma [98] Overexpressed Promotes cell viability
  Hepatocellular carcinoma [19, 86] Overexpressed Associated with poor prognosis
  Lung cancer [87] Overexpressed Associated with poor survival
  Breast cancer [99] Overexpressed Worsens prognosis
  Intrahepatic cholangiocarcinoma [101] Overexpressed Associated with prognosis
  Osteoarthritis [100] Overexpressed Promotes apoptosis
  Esophageal squamous cell carcinoma [88] Overexpressed Associated with poor survival
UBE2F Non-small cell lung cancer [89] Overexpressed Associated with poor survival
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