From: Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors in clinical trials for cancer immunotherapy
Species
CL (mL/min/kg)
Vss (L/kg)
t1/2 (h)
F (%)
Rat
27
3.8
3.9
4
Dog
25
5.7
4.7
39
Cyno
19
4.1
6.6
10